"Misaka Mikoto, a middle-school girl with an amazing and highly-destructive ability to control electricity, is one of the top level espers in Academy City, a highly developed town populated by students with supernatural abilities. Joined by her three very different girl friends - her flirty roommate and skilled teleporting esper Kuroko, Kuroko's innocent rookie partner at the local student-run law enforcing agency, Uiharu, and Uiharu's best friend, Saten, who has no esper powers - Mikoto encounters various strange phenomena and eccentric people through her action-packed adventures in this exciting scientific town.